Targacept to Report Third Quarter 2014 Financial Results on November 5, 2014

Targacept Inc. (NASDAQ: TRGT), a clinical-stage biopharmaceutical company advancing NNR Therapeutics™, today announced that it will report financial results for the third quarter of 2014 on Wednesday, November 5, 2014, before the U.S. financial markets open.

Management will discuss the company’s third quarter financial results, provide a business update, and discuss expectations for the future via conference call at 8:30 a.m. Eastern Standard Time on Wednesday, November 5, 2014. Participants may access the conference call by dialing 866.825.3209 (domestic callers) and 617.213.8061 (international callers). The passcode for the call is 66014811.

A live audio webcast of the conference call will be accessible from the Investor Relations page of Targacept’s website, www.targacept.com. To ensure a timely connection to the webcast, it is recommended that users register at least 15 minutes prior to the scheduled start time. An archived version of the webcast will also be available for replay through the Investor Calendar section of the Investor Relations page of Targacept’s website for at least two weeks following the call.

About Targacept

Targacept is dedicated to building health and restoring independence for patients. For more information, please visit www.targacept.com.