Mixed Markets Over Job Replacement Concerns

The markets traded mixed during the midday with the Dow adding 8 points to 10,582 as a drop in mortgage rates tempered concerns that the nation will have difficulty replacing the 7 million jobs lost over the past two years. Nasdaq dropped 12 points to 2288.

On the upside

Zix (Nasdaq: ZIXI) offered an upbeat preliminary fourth quarter update and announced that it expects 2010 to be its first profitable year.

Cyclacel Pharmaceuticals (Nasdaq: CYCC) reported that its lung cancer treatment seliciclib killed lung cancer cells.

Somaxon Pharmaceuticals (Nasdaq: SOMX) reassured investors that it will continue working with the Food and Drug Administration in seeking approval of its insomnia medication Silenor.

On the downside

ZymoGenetics (Nasdaq: ZGEN) increased its public offering to 14 million common shares at $6 per share.

J.C. Penney (NYSE: JCP) reported a drop in December same store sales.

Analysts downgraded Hot Topic (Nasdaq: HOTT) after the teen apparel retailer reported lower December same store sales and cut its fourth quarter guidance.

In the broad market, declining issues barely edged out advancers by a slim margin on both the NYSE and on Nasdaq. The Russell 2000 which tracks small cap stocks eased a fraction to 637.

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